LRRK2 and Parkinson disease: Similar associations and effect sizes were observed in the subgroups of PD patients, GBA1-PD, LRRK2-PD, and NC-PD (allelic OR = 0.774, CI = 0.615–0.975, p = 0.030; allelic OR = 0.694, CI = 0.515–0.936, p = 0.017; and allelic OR = 0.815, CI = 0.712–0.933, p = 0.003, respectively, Table 3), suggesting a unified protection effect regardless of the carrier status of GBA1 and LRRK2 mutations.