HIF1A and breast cancer: The accumulation of hypoxia-inducible factor 1 (Hif1-α), a primary driver of angiogenesis through the activation of factors like vascular endothelial growth factors (VEGFs), is associated with tumor progression and the emergence of aggressive, treatment-resistant breast cancers of the triple-negative breast-cancer molecular subtype [13,14,15,16,17,18,19].