DNMT3A and thymoma: Genomic alterations were also investigated in a large cohort of patients with TET, and their frequency was found to be significantly higher in TC than in thymomas, with mutations in CDKN2A (39.9%), TP53 (30.2%), and CDKN2B (24.6%) being more frequent in TC than in thymomas (TP53 (7.8%), DNMT3A (6.8%), and CDKN2A (5.8%)) [16].