AFP and adenoma: In the last group, 3/10 patients with an imaging and serological diagnosis of HCC were treated with transarterial chemoembolization (TACE) without a histologically confirmed diagnosis; 1 patient underwent biopsy of the liver mass in another center; an ultrasound and MRI established the differential diagnosis between an adenoma and FNH in 1 patient with low AFP; and 5 patients underwent a biopsy at our center.