Nevertheless, in the context of FALDs, a biopsy has several limitations including sampling error, risk of bleeding and infection, and the need for procedural sedation; therefore, a liver biopsy is at least highly recommended in cases of suspicious imaging (i.e., increase in size, focality, and growth of the nodule as well as the presence of rings or behaviors with wash-in and wash-out in the MRI phases) or high levels of AFP. Here, AFP is linked to infection.