Shi et al. identified the CSF-1R/STAT3/Mir-34a axis as regulator of pro-tumoral functions in CRC, where CSF-1R expression was positively correlated with the expression of EMT-related genes like SNAIL and SLUG, and EMT markers such as vimentin and low expression levels of E-cadherin (Figure 2) [54]. Here, CSF1R is linked to colorectal carcinoma.