Statins are competitive inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-CoA), and they also have potential chemopreventive and cytotoxic effects on cancer cells in different types of cancers, primarily through the inhibition of the mevalonate pathway, independent of their lipid-lowering effect [7,8,9,10]. The gene discussed is HMGCR; the disease is cancer.