In particular, a combined regimen of SFN and 5-fluorouracil (5-FU) has been reported to synergistically inhibit the proliferation of 5-FU-resistant salivary gland adenoid cystic carcinoma ACC-M and ACC-2 cells by targeting NF-κB activity [60]. Here, NFKB1 is linked to adrenal cortex carcinoma.