AR and posterior cortical atrophy: We evaluated the interactions between the upregulated genes in PCa, CRPC AR+ or CRPC AR− (Tables S8 and S10) and the drug targets associated with epigenetic transcription regulation or MAP kinase signal transduction regulation (Table S11) [8,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71].