When investigating the reactivity of LTL with PAP glycans in the seminal plasma of the oligoasthenozoospermic group (median value: 0.17 ± 0.15 AU; pOA = 0.046826), we found a significantly lower LewisX and LewisY motifs expression in comparison to the normozoospermic infertile men (median value: 0.25 ± 0.12 AU). Here, ACP3 is linked to Infertility.