The findings from physicochemical and biochemical studies unveiled that substances such as stilbenes have health-promoting biological effects related to the prevention of coronary heart disease and the reduction of cancer, aligned with the ability to inhibit the enzymatic activity of the nuclear transcription factor NFκB crucial transcriptional mediator in cell activation pathways, involved in the signaling of neoplastic, inflammatory, and degenerative diseases [40]. The gene discussed is NFKB1; the disease is cancer.