Regarding the potential indicating role of ZMIZ2 in clinical prognosis, Kaplan-Meier survival analysis showed that higher ZMIZ2 expression was associated with shorter overall survival times (Fig. 1I), and subsequent univariate Cox regression analysis indicated that ZMIZ2 expression was a risk factor for HCC prognosis (Table 1). The gene discussed is ZMIZ2; the disease is hepatocellular carcinoma.