NLGN3 and glioblastoma: We also showed that co-overexpression of KPNB1 and knockdown of NLGN3 attenuated the downregulation of NLGN3 expression caused by NLGN3 silencing alone (Supplementary Fig. S2A and S2B), as well as the inhibitory effect of NLGN3 silencing alone on GBM cell lines (Supplementary Fig. S2C-E).