WT1 and acute myeloid leukemia: Therefore, we designed a custom NGS-based DNA methylation panel comprising of loci/genes from selected studies as well as genes generally connected to AML pathogenesis such as HOX genes and WT1. Apart from our recent study [7] that validated individual DNA methylation changes and utilized the same AML cohort as well as the DNA methylation sequencing panel, we now wanted to evaluate all potential epigenetic markers comprehensively at once.