Some genes closely related to mild-to-moderate HL have been reported, such as Stereocilin (STRC, MIM: 606440), Otogelin (OTOG, MIM: 604487), Otogelin-like protein (OTOGL, MIM: 614925), Myelin protein zero-like 2 (MPZL2, MIM: 604873), Otoancorin (OTOA, MIM: 607038), and Alpha-tectorin (TECTA, MIM:602574) [6–11]. This evidence concerns the gene OTOA and Hodgkins lymphoma.