Not only is stromal TEM1 involved in the progression of cancers, such as abdominal tumors, breast cancer, hepatocellular carcinoma, and osteosarcoma [46, 81, 95], but it is also involved in tissue repair and scarring, including kidney fibrosis, liver fibrosis, adipocyte tissue fibrosis, atherosclerosis, and cutaneous wound healing [22, 36, 72]. Here, CD248 is linked to Hepatic fibrosis.