ScRNA-seq analysis identified consistent expression patterns for TEM1, ACTA2, COL1A1, FN1, TGFBR1, and TGFBR2 in distinct fibroblast subsets of both keloids (Fig. 2 and Additional file 1: Fig. S4) and hypertrophic scars (Additional file 1: Fig. S6). The gene discussed is COL1A1; the disease is keloid.