MKI67 and neoplasm: Multifactorial analysis revealed tumor size (P < 0.001), hyperechoic halo (P < 0.001), shape (P = 0.018), posterior acoustic enhancement (P = 0.002), shadowing (P = 0.007), and suspicious axillary ultrasound performance (P = 0.031) as independent predictors associated with high lymph node burden; ki67, molecular subtype, and combined pattern in posterior features were not significant factors (Table 3).