The expression of BMI1, ITGB1, and PXN-AS1 in 30 patients without lymph node metastasis was compared with 30 patients with lymph node metastasis, and only the expression of BMI1 and ITGB1 was further elevated in the tumor tissues of patients with lymph node metastasis (Fig. 3C). The gene discussed is BMI1; the disease is metastatic malignant neoplasm in the lymph nodes.