SH3KBP1 and cancer: Besides, SH3KBP1(ranked 10th in patient TCGA-BH-A1FD) was reported to serve as a new regulator of carcinogenic EGFR (Epidermal Growth Factor Receptor), and it could also serve as a potential therapy target for GBM (Glioblastoma multiforme, a kind of cancer) patients with EGFR activation [65].