AKT1 and COVID-19: As for KEGG analysis, our data revealed that upregulated DEGs were highly linked to ECM-receptor interaction, focal adhesion, PI3K-Akt signaling pathway, regulation of actin cytoskeleton and Rap1 signaling pathway (Fig. 4E), whereas downregulated DEGs in glutathione metabolism, cytokine-cytokine receptor interaction and coronavirus disease - COVID-19 (Fig. 4G).