MMP12 and preeclampsia: Concerning late-onset preeclampsia, we found associations with the variables BNP, MMP-12, IDUA, first-trimester systolic blood pressure, PlGF, low-affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B), and T cell surface glycoprotein (CD4), presented in descending order of their median importance (Fig. 3).