Out of these 29 genetic biomarkers, two were tested in more than one study (rs10911021 on GLUL, GRS for CHD [GRS-CHD]), one had improvement in any performance indicator in a single study (isoform e4 in APOE), and one had improvement in all three performance indicators in a single study (GRS-CHD) (Fig. 7). This evidence concerns the gene APOE and coronary artery disorder.