NPM1 and acute myeloid leukemia: To address the question whether enrichment of interferon signaling and metabolic pathways were associated with shorter EFS in other AML subtypes, we analyzed RNA-seq data from 60 AML patients with NPM1 mutation and compared the transcriptomes between patients with short EFS (EFS < 2 years, n = 34) and those with long EFS (n = 26).