SLC4A11 and congenital hereditary endothelial dystrophy of cornea: With an onset at birth or in early childhood, CHED has an autosomal recessive inheritance pattern and is associated with over 90 distinct mutations in the solute linked carrier family 4 member 11 (SLC4A11) gene, in which approximately 80 percent of affected individuals harbor homozygous or compound heterozygous mutations [2–20].