Tanaka revealed that high-purity omega-3 polyunsaturated fatty acids (n-3 PUFAs) alleviated NASH patients as indicated by liver fat, liver enzymes, or markers of inflammation, while a study from Kenneth showed that ARRB1 variants may influence the response to antidepressant drugs in depressed patients (Chappell et al. 2022; Tanaka et al. 2008). This evidence concerns the gene ARRB1 and metabolic dysfunction-associated steatohepatitis.