E-Selectin, ICAM-1 and VCAM-1 are adhesion molecules expressed on the surface of vascular endothelial cells, and they mediate the developmental mechanisms of atherosclerosis, such as the binding and recruitment of vascular endothelial cells to circulating leukocytes, and migration to the subcutaneous region [74,75]. The gene discussed is VCAM1; the disease is atherosclerosis.