CD276 and neoplasm: In terms of prognosis, Zhan et al. demonstrated patients with increased B7-H3 expression had significantly worse prognosis (p = 0.012), while the OS of the B7-H3 high group was poorer compared to B7-H3 low group, for both tumor and stromal expression (p = 0.007 and p = 0.048, respectively) [93].