ERCC3 and cancer: Among these drugs are substances that preferentially kill cancer cells—for example, inhibitors of the RNA pol II itself, such as actinomycin D and α-amanitin [10]; inhibitors of the transcription and DNA repair complex TFIIH, such as triptolide (TPL) and THZ1; inhibitors of the PTEFb complex such as flavopiridol; and others that affect transcription [11,12,13,14].