CASP1 and familial dilated cardiomyopathy: In vivo and in vitro experiments confirmed that the expression of miRNA-30d in the diabetic group was significantly increased, and its increased expression up-regulated the expression of pro-inflammatory factors such as Caspase-1 and IL-1βand directly inhibited the expression of foxo3a and its downstream proteins, which promoted the pyroptosis of cardiomyocytes in DCM.