also found that miR-223 is highly expressed in H9C2 cardiomyocytes induced by high glucose, and the use of miR-223 inhibitors can attenuate the activation of NLRP3 inflammasome and alleviate myocardial fibrosis, thereby delaying the development of DCM and protecting the heart (154). Here, NLRP3 is linked to familial dilated cardiomyopathy.