H19 and atherosclerosis: For instance, the lncRNAs H19, TUG1, and Neat1 are upregulated in atherosclerosis and contribute to vascular smooth muscle cell (VSMC) proliferation while inhibiting apoptosis On the other hand, the downregulation of UCA1, MEG3, lincRNA-p21, and GASL1 in atherosclerosis leads to suppressed VSMC proliferation and inflammation8, 38-40.