The HDL and uric acidconcentrations were shown significantly decreased in T2DM with CAD after 5 years when compared to newly diagnosed CAD in T2DM, (P<0.05).the inflammatory cytokine interleukin - 6 was significantly elevated in T2DM with CAD after 5 years than the newly diagnosed CAD in T2DMpatients, respectively P value is 0.001** (Table 1). Here, IL6 is linked to coronary artery disorder.