P4HA1 and obstructive sleep apnea syndrome: Given that P4HA1 is a risk factor in OSA, molecular docking analysis was employed to identify the interaction structure between P4HA1 and three first-line chemotherapy drugs (Adriamycin, Ifosfamide, Methotrexate), which might can provide an important theoretical reference for targeting P4HA1 (Figure 7C).