CD8A and neoplasm: Further, a positive correlation was seen between autoradiography brain concentration and in vivo [89Zr]-CD8 minibody ImmunoPET SUVmean quantification (r = 0.45, p < 0.01), see Figure 5B. In addition, ImmunoPET metrics were positively correlated to intratumoral CD8+ cell infiltration (r = 0.55, p < 0.001), as shown by Figure 5C. Finally, BLI signal was confirmed to be indicative of tumor burden as shown by the strong positive correlation with total tumor area quantified from H&E staining (r = 0.86, p < 0.0001), see Figure 5D.