Then, we also measured miR-5193 level in TT-EVs from 73 lung cancer patients (Table S2) and found that the TT-EV miR-5193 level was positively correlated with the CCL21 level and the numbers of CD11c+ DCs, CD4+ T cells and CD8+ T cells in tumor tissues and that the CCL21 level and DC number were also positively correlated (Figure 5G and Figure S5E). This evidence concerns the gene CD8A and lung cancer.