However, only SDSL showed an AUC value greater than 0.7 in the test set, whereas EGFL7, SMTNL2, MFAP4, TAGLN, SGPP2 and SMTNL2 showed AUC values greater than 0.5, so SDSL may be a high risk factor in patients with heart failure (Figure 4). The gene discussed is SMTNL2; the disease is heart failure.