Age, height, weight, BMI, etiology of HF, clinical history (DM, hyperuricemia, smoking, AF, MI, hospitalization for HF, cancer), NYHA, DBP, heart rate, left ventricular diastolic dimension, LVEF, hemoglobin, albumin, eGFR, LDL-C, BNP, previous treatments (PCI, CABG, PMI), medications at baseline (antiplatelet, aldosterone antagonist, beta-blocker, ACE inhibitor and/or ARB, ACE inhibitor, diuretic). The gene discussed is ACE; the disease is diabetes mellitus.