DLST and Familial prostate cancer: Intriguingly, dihydrolipoamide S-succinyl-transferase (E2 component of 2-oxo-glutarate complex) (DLST), a metabolic enzyme of Krebs cycle [65], was upregulated in MCF-7 breast cancer cells (Table 1), but downregulated in PC3 prostate cancer cells (Table 2).