The proteomic dataset showed the elevated expression of tumour protein D53 (hD53 encoded by TPD52L1) and tumour protein D54 (hD54 encoded by TPD52L2) of MCF-7 breast cancer cells in response to the change of extracellular zinc (Table 1), which explains to some extent why zinc promotes breast cancer growth. This evidence concerns the gene TPD52L1 and breast cancer.