The proteomic dataset showed the elevated expression of tumour protein D53 (hD53 encoded by TPD52L1) and tumour protein D54 (hD54 encoded by TPD52L2) of MCF-7 breast cancer cells in response to the change of extracellular zinc (Table 1), which explains to some extent why zinc promotes breast cancer growth. The gene discussed is TPD52L2; the disease is breast cancer.