LBP and obesity due to melanocortin 4 receptor deficiency: The serum level of LBP was positively correlated with TG, and some studies have shown that a higher serum level of LBP is associated with the risks of obesity, metabolic syndrome, type 2 diabetes and atherosclerosis (49, 50), which may be related to the innate immune response triggered by LBP leads to metabolic disturbances (51).