NR3C1 and Anxiety: In a nested case-control study involving Chinese university students (cases, n = 50; controls, n = 100), NR3C1-16 CpG 10 methylation was found to significantly mediate the correlation between academic stress and anxiety symptoms, suggesting that NR3C1-16 CpG 10 DNA methylation could be a potential mechanism underlying adolescent anxiety (Hua et al., 2023).