A Marchak bootay extract that is rich in saturated fatty acids and flavonoids (apigenin, kaempferol, luteolin, apigenin-7-O-glucoside) showed excellent pharmacological safety in vivo. Ahmad and colleagues iterated the benefits and targets of various fractions of marchak in the context of NFκB inhibition, NO activity, and antiproliferative activity in neuroblastoma cells[68]. The gene discussed is NFKB1; the disease is neuroblastoma.