Furthermore, compared with ICU-acquired infection patients, co-infection group had a significantly higher levels of serum IL-6 (9.58 [6.02–54.61] vs. 0.00 [0.00–29.64], p = 0.022) and IL-10 (34.37 [12.79–693.04] vs. 9.86 [2.79–44.64], p = 0.034) (Table 2). This evidence concerns the gene IL10 and coinfection.