In summary, four genes (SLC34A2, TRPV6, FCGR2A, and ATP1A3) were upregulated under high adenine diet-induced CKD (Figure 5D), while 10 genes (SLC5A1, SLC34A1, VDR, SLC34A3, SLC30A1, ATP7B, SLC6A19, SLC9A3, ATP2B2, and S100G) were downregulated (Figure 5E). This evidence concerns the gene ATP1A3 and chronic kidney disease.