NLRP3 and viral infectious disease: When the NLRP3 inflammasome is activated by virus infection, it disrupts the replication niche within the pathogen cell, thereby promoting the release of proinflammatory factors; this, in turn, leads to the activation of a highly inflammatory form of cell death, namely pyroptosis; subsequently, it plays a barrier role in innate immunity (Miao et al., 2010; Shi et al., 2017).