In patients with septic shock, up to 65% of those with an elevated hs-cTnI level have various cardiac dysfunctions on transthoracic echocardiography and, more than the baseline level, a maximum change in hs-cTnI and ST waves-T on the electrocardiogram can be considered a risk factor for the development of SIMD [13]. The gene discussed is TNNI3; the disease is septic shock.