HMGCR and metabolic dysfunction-associated steatohepatitis: When gene analysis was performed, genes involved with cholesterol synthesis (i.e., HMGCR increased), clearance (LDL-R reduced), and those involved in the synthesis of bile (CYP 7A1/27A reduced) or transport (ABCG1/8 reduced) were altered, which may have resulted in higher FC in MASH patients.