INS and chronic kidney disease: Furthermore, at the moment of the PET/CT scan, 133 patients were using insulin replacement therapy; no significant differences in terms of the use of this therapy were underlined between patients with CKD and the controls (p-value 0.773), between subjects with a Cr value below and above 1.2 mg/dL (p-value 0.913) and between subjects with an EGFR below and above 60 mL/min/1.73 m2 (p-value 0.676).