Rove et al. also found that hs-CRP was negatively linked to the relationship between the amount of HDL cholesterol as well as the sensitivity to insulin index while being positively related to waist circumference, body mass index (BMI), high blood pressure, cholesterol, triglycerides, LDL cholesterol, glucose levels in the plasma and fasting insulin in the “Insulin Resistance and Atherosclerosis Study (IRAS)” [32]. The gene discussed is CRP; the disease is Insulin resistance.