However, if a biopsy from a clinically suspected patient of AIH has unusually prominent biliary features, such as bile duct loss or features of chronic cholestasis (e.g., periportal deposits of copper, copper-associated protein, or periportal keratin 7-positive cells with an intermediate hepatobiliary phenotype), possibility of PBC or PSC with AIH-like features may be considered [35]. The gene discussed is KRT7; the disease is autoimmune hepatitis.