Another important aim was to determine the IDH mutational status in a series of 96 intracranial chondroid tumors, including chondrosarcomas, chordomas, osteosarcomas, chondromas, and chondromyxoid fibromas in order to evaluate the diagnostic utility of IDH1/2 mutations for these types of neoplasms. This evidence concerns the gene IDH1 and chondromyxoid fibroma.