IDH1 and chondrosarcoma: Nevertheless, the detection rate of the IDH1 mutation was almost similar for all three methods in the whole sample of 96 tumors (36%, 36%, and 37%, see Table 4), but in chondrosarcomas, qPCR-DMA-Sanger showed a slightly lower sensitivity (46%) compared to biochip (48.3%) or IHC (48.2%) methods.