TGFB1 and idiopathic pulmonary fibrosis: In the present study, to better understand how they behave in a profibrotic environment, we analyzed the response of LR-MSC from patients with IPF compared with those isolated from controls to profibrotic stimuli, both in vivo, using an experimental model of BLM, and in vitro, exposing LR-MSC to TGFβ.