CCL20 and blood coagulation disease: Our investigations revealed an immunological signature associated with subclinical CAA in ART-treated PLWH, including (i) increased plasma CCL20 levels (indicative of systemic immune activation); (ii) reduced Th17/Treg ratios (reflecting ongoing alterations in mucosal barrier integrity); (iii) increased frequencies of non-classical CD16+ monocytes with a CCR9lowHLA-DRhigh phenotype (exerting pro-inflammatory features); and (iv) increased plasma fibrinogen levels (sign of coagulopathy).